Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts

The pleiotropic cytokine IL-6 accelerates the progression of breast cancer in a variety of preclinical models through the activation of the STAT3 (signal transducer and activator of transcription 3) signaling pathway. However, the proportion of breast cancers sensitive to anti-IL-6 therapies is not...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Morancho, Beatriz, Zacarías-Fluck, Mariano, Esgueva, Antonio, Bernadó-Morales, Cristina, Cosimo, Serena Di, Prat, Aleix, Cortés, Javier, Arribas, Joaquín, Rubio, Isabel T.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356531/
https://ncbi.nlm.nih.gov/pubmed/27602583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11815
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