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Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts
The pleiotropic cytokine IL-6 accelerates the progression of breast cancer in a variety of preclinical models through the activation of the STAT3 (signal transducer and activator of transcription 3) signaling pathway. However, the proportion of breast cancers sensitive to anti-IL-6 therapies is not...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5356531/ https://ncbi.nlm.nih.gov/pubmed/27602583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11815 |
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