Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis

Oncogenic transformation triggers reprogramming of cell metabolism, as part of the tumorigenic process. However, metabolic reprogramming may also increase the sensitivity of transformed cells to microenvironmental stress, at the early stages of tumor development. Herein, we show that transformation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Martín-Pérez, Rosa, Yerbes, Rosario, Mora-Molina, Rocío, Cano-González, Ana, Arribas, Joaquín, Mazzone, Massimiliano, López-Rivas, Abelardo, Palacios, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706828/
https://ncbi.nlm.nih.gov/pubmed/29212182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21458
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados