Control of FLIP(L) expression and TRAIL resistance by the extracellular signal-regulated kinase1/2 pathway in breast epithelial cells

Increased activation of the epidermal growth factor receptor (EGFR) is frequently observed in tumors, and inhibition of the signaling pathways originated in the EGFR normally renders tumor cells more sensitive to apoptotic stimuli. However, we show that inhibition of EGFR signaling in non-transforme...

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Main Authors: Yerbes, R, López-Rivas, A, Reginato, M J, Palacios, C
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504708/
https://ncbi.nlm.nih.gov/pubmed/22722337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.78
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