Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis

Oncogenic transformation triggers reprogramming of cell metabolism, as part of the tumorigenic process. However, metabolic reprogramming may also increase the sensitivity of transformed cells to microenvironmental stress, at the early stages of tumor development. Herein, we show that transformation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Martín-Pérez, Rosa, Yerbes, Rosario, Mora-Molina, Rocío, Cano-González, Ana, Arribas, Joaquín, Mazzone, Massimiliano, López-Rivas, Abelardo, Palacios, Carmen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706828/
https://ncbi.nlm.nih.gov/pubmed/29212182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21458
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