HER2 Carboxyl-terminal Fragments Regulate Cell Migration and Cortactin Phosphorylation

A group of breast cancer patients with a higher probability of developing metastasis expresses a series of carboxyl-terminal fragments (CTFs) of the tyrosine kinase receptor HER2. One of these fragments, 611-CTF, is a hyperactive form of HER2 that constitutively establishes homodimers maintained by...

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Hlavní autoři: García-Castillo, Jesús, Pedersen, Kim, Angelini, Pier-Davide, Bech-Serra, Joan Josep, Colomé, Núria, Cunningham, Matthew Paul, Parra-Palau, Josep Lluis, Canals, Francesc, Baselga, José, Arribas, Joaquín
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757232/
https://ncbi.nlm.nih.gov/pubmed/19589785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001982
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