Mapping of the CD23 Binding Site on Immunoglobulin E (IgE) and Allosteric Control of the IgE-FcϵRI Interaction

IgE, the antibody that mediates allergic responses, acts as part of a self-regulating protein network. Its unique effector functions are controlled through interactions of its Fc region with two cellular receptors, FcϵRI on mast cells and basophils and CD23 on B cells. IgE cross-linked by allergen t...

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Detaylı Bibliyografya
Asıl Yazarlar: Borthakur, Susmita, Hibbert, Richard G., Pang, Marie O. Y., Yahya, Norhakim, Bax, Heather J., Kao, Michael W., Cooper, Alison M., Beavil, Andrew J., Sutton, Brian J., Gould, Hannah J., McDonnell, James M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438978/
https://ncbi.nlm.nih.gov/pubmed/22815482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.397059
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