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IgE signaling suppresses FcεRIβ expression

Activation of the high-affinity receptor for IgE, FcεRI, is known to elicit its rapid down-regulation through internalization and degradation. In keeping with this, expression of all three FcεRI subunits is decreased at the protein level after cross-linkage of IgE with antigen. However, we find that...

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Autori principali: Brenzovich, Jennifer, Macey, Matthew, Fernando, Josephine, Chong, Hey Jin, Barnstein, Brian, Mirmonsef, Paria, Morales, Johanna K., Kimura, Akiko, Cruz, Tracey Dawson, Ryan, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Society for Leukocyte Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780917/
https://ncbi.nlm.nih.gov/pubmed/19741159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0409231
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