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IgE binds asymmetrically to its B cell receptor CD23

The antibody IgE plays a central role in allergic disease mechanisms. Its effector functions are controlled through interactions between the Fc region and two principal cell surface receptors FcεRI and CD23. The interaction with FcεRI is primarily responsible for allergic sensitization and the infla...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Dhaliwal, Balvinder, Pang, Marie O. Y., Keeble, Anthony H., James, Louisa K., Gould, Hannah J., McDonnell, James M., Sutton, Brian J., Beavil, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374546/
https://ncbi.nlm.nih.gov/pubmed/28361904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45533
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