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IgE binds asymmetrically to its B cell receptor CD23

The antibody IgE plays a central role in allergic disease mechanisms. Its effector functions are controlled through interactions between the Fc region and two principal cell surface receptors FcεRI and CD23. The interaction with FcεRI is primarily responsible for allergic sensitization and the infla...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dhaliwal, Balvinder, Pang, Marie O. Y., Keeble, Anthony H., James, Louisa K., Gould, Hannah J., McDonnell, James M., Sutton, Brian J., Beavil, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374546/
https://ncbi.nlm.nih.gov/pubmed/28361904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45533
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