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Soluble CD23 Controls IgE Synthesis and Homeostasis in Human B Cells
CD23, the low affinity receptor for IgE, exists in membrane and soluble forms. Soluble CD23 fragments are released from membrane CD23 by the endogenous metalloprotease, ADAM10. When purified tonsil B cells are incubated with IL-4 and anti-CD40 to induce class switching to IgE in vitro, membrane CD23...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378639/ https://ncbi.nlm.nih.gov/pubmed/22393152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102689 |
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