Soluble CD23 Controls IgE Synthesis and Homeostasis in Human B Cells

CD23, the low affinity receptor for IgE, exists in membrane and soluble forms. Soluble CD23 fragments are released from membrane CD23 by the endogenous metalloprotease, ADAM10. When purified tonsil B cells are incubated with IL-4 and anti-CD40 to induce class switching to IgE in vitro, membrane CD23...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cooper, Alison M., Hobson, Philip S., Jutton, Mark R., Kao, Michael W., Drung, Binia, Schmidt, Boris, Fear, David J., Beavil, Andrew J., McDonnell, James M., Sutton, Brian J., Gould, Hannah J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378639/
https://ncbi.nlm.nih.gov/pubmed/22393152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102689
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