IgE Trimers Drive SPE-7 Cytokinergic Activity

Degranulation of mast cells and basophils, with release of agents of the allergic response, ensues when multivalent antigens bind to and cross-link the cells’ receptor-bound IgE antibodies. A widely used commercial monoclonal IgE antibody, SPE-7 IgE from Sigma, was found to possess the radically ano...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Bax, Heather J., Bowen, Holly, Beavil, Rebecca L., Chung, Raymond, Ward, Malcolm, Davies, Anna M., Dodev, Tihomir S., McDonnell, James M., Beavil, Andrew J., Sutton, Brian J., Gould, Hannah J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557881/
https://ncbi.nlm.nih.gov/pubmed/28811536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08212-6
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