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IgE binds asymmetrically to its B cell receptor CD23

The antibody IgE plays a central role in allergic disease mechanisms. Its effector functions are controlled through interactions between the Fc region and two principal cell surface receptors FcεRI and CD23. The interaction with FcεRI is primarily responsible for allergic sensitization and the infla...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Dhaliwal, Balvinder, Pang, Marie O. Y., Keeble, Anthony H., James, Louisa K., Gould, Hannah J., McDonnell, James M., Sutton, Brian J., Beavil, Andrew J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374546/
https://ncbi.nlm.nih.gov/pubmed/28361904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45533
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