Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI

Por Dhaliwal, Balvinder, Yuan, Daopeng, Pang, Marie O. Y., Henry, Alistair J., Cain, Katharine, Oxbrow, Amanda, Fabiane, Stella M., Beavil, Andrew J., McDonnell, James M., Gould, Hannah J., Sutton, Brian J.
Publicado em 2012

Human immunoglobulin E flexes between acutely bent and extended conformations

Por Drinkwater, Nyssa, Cossins, Ben, Keeble, Anthony H, Wright, Michael, Cain, Katharine, Hailu, Hanna, Oxbrow, Amanda, Delgado, Jean, Shuttleworth, Lindsay K, Kao, Michael W-P, McDonnell, James M, Beavil, Andrew J, Henry, Alistair J, Sutton, Brian J
Publicado em 2014

A Mixture of Functionally Oligoclonal Humanized Monoclonal Antibodies That Neutralize Clostridium difficile TcdA and TcdB with High Levels of In Vitro Potency Shows In Vivo Protect...

Por Davies, Nicola L., Compson, Joanne E., MacKenzie, Brendon, O'Dowd, Victoria L., Oxbrow, Amanda K. F., Heads, James T., Turner, Alison, Sarkar, Kaushik, Dugdale, Sarah L., Jairaj, Mark, Christodoulou, Louis, Knight, David E. O., Cross, Amanda S., Hervé, Karine J. M., Tyson, Kerry L., Hailu, Hanna, Doyle, Carl B., Ellis, Mark, Kriek, Marco, Cox, Matthew, Page, Matthew J. T., Moore, Adrian R., Lightwood, Daniel J., Humphreys, David P.
Publicado em 2013