Mutations in the DG Loop of Adenovirus Type 5 Fiber Knob Protein Abolish High-Affinity Binding to Its Cellular Receptor CAR

The amino acid residues in adenovirus type 5 (Ad5) fiber that interact with its cellular receptor, the coxsackie B virus and Ad receptor (CAR), have not been defined. To investigate this, multiple mutations were constructed in the region between residues 479 and 497 in Ad5 fiber (β-strands E and F a...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kirby, Ian, Davison, Elizabeth, Beavil, Andrew J., Soh, Cecilia P. C., Wickham, Thomas J., Roelvink, Peter W., Kovesdi, Imre, Sutton, Brian J., Santis, George
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10516059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.11.9508-9514.1999
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