The Epstein-Barr Virus-encoded G Protein-coupled Receptor BILF1 Hetero-oligomerizes with Human CXCR4, Scavenges Gα(i) Proteins, and Constitutively Impairs CXCR4 Functioning

Por Nijmeijer, Saskia, Leurs, Rob, Smit, Martine J., Vischer, Henry F.
Publicado em 2010

G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?

Por Vischer, Henry F, Watts, Anne O, Nijmeijer, Saskia, Leurs, Rob
Publicado em 2011

Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors

Por de Munnik, Sabrina M., Smit, Martine J., Leurs, Rob, Vischer, Henry F.
Publicado no Front Pharmacol (2015)

The far carboxy-terminus of the viral encoded chemokine receptor US28 binds to the sorting protein GASP-1 in vitro

Por Parzmair, Gerald P, Platzer, Wolfgang, Vischer, Henry F, Smit, Martine J, Waldhoer, Maria
Publicado em 2008

Bioluminescence Resonance Energy Transfer Based G Protein-Activation Assay to Probe Duration of Antagonism at the Histamine H(3) Receptor

Por Mocking, Tamara A. M., Buzink, Maurice C. M. L., Leurs, Rob, Vischer, Henry F.
Publicado no Int J Mol Sci (2019)

Development of a Conformational Histamine H(3) Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists

Por Schihada, Hannes, Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar, Leurs, Rob, Pockes, Steffen, Lohse, Martin J.
Publicado no ACS Sens (2020)

The Target Residence Time of Antihistamines Determines Their Antagonism of the G Protein-Coupled Histamine H1 Receptor

Por Bosma, Reggie, Witt, Gesa, Vaas, Lea A. I., Josimovic, Ivana, Gribbon, Philip, Vischer, Henry F., Gul, Sheraz, Leurs, Rob
Publicado no Front Pharmacol (2017)

Function-specific virtual screening for GPCR ligands using a combined scoring method

Por Kooistra, Albert J., Vischer, Henry F., McNaught-Flores, Daniel, Leurs, Rob, de Esch, Iwan J. P., de Graaf, Chris
Publicado no Sci Rep (2016)

The sorting protein GASP-1 regulates the constitutive signaling capacity of the virally encoded chemokine receptor US28

Por Tschische, Pia, Moser, Elisabeth, Thompson, Dawn, Platzer, Wolfgang, Vischer, Henry, Smit, Martine J, Schaider, Helmut, Martini, Lene, Whistler, Jennifer, Waldhoer, Maria
Publicado em 2009

Differential Role of Serines and Threonines in Intracellular Loop 3 and C-Terminal Tail of the Histamine H(4) Receptor in β-Arrestin and G Protein-Coupled Receptor Kinase Interacti...

Por Verweij, Eléonore W. E., Al Araaj, Betty, Prabhata, Wimzy R., Prihandoko, Rudi, Nijmeijer, Saskia, Tobin, Andrew B., Leurs, Rob, Vischer, Henry F.
Publicado no ACS Pharmacol Transl Sci (2020)

Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28

Por Langemeijer, Ellen V., Slinger, Erik, de Munnik, Sabrina, Schreiber, Andreas, Maussang, David, Vischer, Henry, Verkaar, Folkert, Leurs, Rob, Siderius, Marco, Smit, Martine J.
Publicado em 2012

The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines

Por de Munnik, Sabrina M., Kooistra, Albert J., van Offenbeek, Jody, Nijmeijer, Saskia, de Graaf, Chris, Smit, Martine J., Leurs, Rob, Vischer, Henry F.
Publicado no PLoS One (2015)

A Photoswitchable Agonist for the Histamine H(3) Receptor, a Prototypic Family A G‐Protein‐Coupled Receptor

Por Hauwert, Niels J., Mocking, Tamara A. M., Da Costa Pereira, Daniel, Lion, Ken, Huppelschoten, Yara, Vischer, Henry F., De Esch, Iwan J. P., Wijtmans, Maikel, Leurs, Rob
Publicado no Angew Chem Int Ed Engl (2019)

Covalent Inhibition of the Histamine H(3) Receptor

Por Wágner, Gábor, Mocking, Tamara A. M., Kooistra, Albert J., Slynko, Inna, Ábrányi-Balogh, Péter, Keserű, György M., Wijtmans, Maikel, Vischer, Henry F., de Esch, Iwan J. P., Leurs, Rob
Publicado no Molecules (2019)

The G-protein Coupled Receptor Associated Sorting Protein GASP-1 Regulates the Signalling and Trafficking of the Viral Chemokine Receptor US28

Por Tschische, Pia, Moser, Elisabeth, Thompson, Dawn, Vischer, Henry F., Parzmair, Gerald P., Pommer, Veronika, Platzer, Wolfgang, Schwarzbraun, Thomas, Schaider, Helmut, Smit, Martine J., Martini, Lene, Whistler, Jennifer L., Waldhoer, Maria
Publicado em 2010

Development of novel fluorescent histamine H(1)-receptor antagonists to study ligand-binding kinetics in living cells

Por Stoddart, Leigh A., Vernall, Andrea J., Bouzo-Lorenzo, Monica, Bosma, Reggie, Kooistra, Albert J., de Graaf, Chris, Vischer, Henry F., Leurs, Rob, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado no Sci Rep (2018)

A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light

Por Gómez-Santacana, Xavier, de Munnik, Sabrina M, Mocking, Tamara A M, Hauwert, Niels J, Sun, Shanliang, Vijayachandran, Prashanna, de Esch, Iwan J P, Vischer, Henry F, Wijtmans, Maikel, Leurs, Rob
Publicado no Beilstein J Org Chem (2019)

Probe dependency in the determination of ligand binding kinetics at a prototypical G protein-coupled receptor

Por Bosma, Reggie, Stoddart, Leigh A., Georgi, Victoria, Bouzo-Lorenzo, Monica, Bushby, Nick, Inkoom, Loretta, Waring, Michael J., Briddon, Stephen J., Vischer, Henry F., Sheppard, Robert J., Fernández-Montalván, Amaury, Hill, Stephen J., Leurs, Rob
Publicado no Sci Rep (2019)

Route to Prolonged Residence Time at the Histamine H(1) Receptor: Growing from Desloratadine to Rupatadine

Por Bosma, Reggie, Wang, Zhiyong, Kooistra, Albert J., Bushby, Nick, Kuhne, Sebastiaan, van den Bor, Jelle, Waring, Michael J., de Graaf, Chris, de Esch, Iwan J., Vischer, Henry F., Sheppard, Robert J., Wijtmans, Maikel, Leurs, Rob
Publicado no J Med Chem (2019)

β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

Por Watts, Anne O., Verkaar, Folkert, van der Lee, Miranda M. C., Timmerman, Claudia A. W., Kuijer, Martien, van Offenbeek, Jody, van Lith, Lambertus H. C. J., Smit, Martine J., Leurs, Rob, Zaman, Guido J. R., Vischer, Henry F.
Publicado em 2013