Development of a Conformational Histamine H(3) Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists

[Image: see text] The histamine H(3) receptor (H(3)R) represents a highly attractive drug target for the treatment of various central nervous system disorders, but the discovery of novel H(3)R targeting compounds relies on the assessment of highly amplified intracellular signaling events that do not...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:ACS Sens
Main Authors: Schihada, Hannes, Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar, Leurs, Rob, Pockes, Steffen, Lohse, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325232/
https://ncbi.nlm.nih.gov/pubmed/32397705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.0c00397
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares