Development of a Conformational Histamine H(3) Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists

[Image: see text] The histamine H(3) receptor (H(3)R) represents a highly attractive drug target for the treatment of various central nervous system disorders, but the discovery of novel H(3)R targeting compounds relies on the assessment of highly amplified intracellular signaling events that do not...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:ACS Sens
Huvudupphovsmän: Schihada, Hannes, Ma, Xiaoyuan, Zabel, Ulrike, Vischer, Henry F., Schulte, Gunnar, Leurs, Rob, Pockes, Steffen, Lohse, Martin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2020
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325232/
https://ncbi.nlm.nih.gov/pubmed/32397705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.0c00397
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk