The Epstein-Barr Virus-encoded G Protein-coupled Receptor BILF1 Hetero-oligomerizes with Human CXCR4, Scavenges Gα(i) Proteins, and Constitutively Impairs CXCR4 Functioning

Por Nijmeijer, Saskia, Leurs, Rob, Smit, Martine J., Vischer, Henry F.
Publicado em 2010

G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand?

Por Vischer, Henry F, Watts, Anne O, Nijmeijer, Saskia, Leurs, Rob
Publicado em 2011

Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors

Por de Munnik, Sabrina M., Smit, Martine J., Leurs, Rob, Vischer, Henry F.
Publicado no Front Pharmacol (2015)

The far carboxy-terminus of the viral encoded chemokine receptor US28 binds to the sorting protein GASP-1 in vitro

Por Parzmair, Gerald P, Platzer, Wolfgang, Vischer, Henry F, Smit, Martine J, Waldhoer, Maria
Publicado em 2008

The Target Residence Time of Antihistamines Determines Their Antagonism of the G Protein-Coupled Histamine H1 Receptor

Por Bosma, Reggie, Witt, Gesa, Vaas, Lea A. I., Josimovic, Ivana, Gribbon, Philip, Vischer, Henry F., Gul, Sheraz, Leurs, Rob
Publicado no Front Pharmacol (2017)

Function-specific virtual screening for GPCR ligands using a combined scoring method

Por Kooistra, Albert J., Vischer, Henry F., McNaught-Flores, Daniel, Leurs, Rob, de Esch, Iwan J. P., de Graaf, Chris
Publicado no Sci Rep (2016)

The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines

Por de Munnik, Sabrina M., Kooistra, Albert J., van Offenbeek, Jody, Nijmeijer, Saskia, de Graaf, Chris, Smit, Martine J., Leurs, Rob, Vischer, Henry F.
Publicado no PLoS One (2015)

The G-protein Coupled Receptor Associated Sorting Protein GASP-1 Regulates the Signalling and Trafficking of the Viral Chemokine Receptor US28

Por Tschische, Pia, Moser, Elisabeth, Thompson, Dawn, Vischer, Henry F., Parzmair, Gerald P., Pommer, Veronika, Platzer, Wolfgang, Schwarzbraun, Thomas, Schaider, Helmut, Smit, Martine J., Martini, Lene, Whistler, Jennifer L., Waldhoer, Maria
Publicado em 2010

Development of novel fluorescent histamine H(1)-receptor antagonists to study ligand-binding kinetics in living cells

Por Stoddart, Leigh A., Vernall, Andrea J., Bouzo-Lorenzo, Monica, Bosma, Reggie, Kooistra, Albert J., de Graaf, Chris, Vischer, Henry F., Leurs, Rob, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Publicado no Sci Rep (2018)

β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

Por Watts, Anne O., Verkaar, Folkert, van der Lee, Miranda M. C., Timmerman, Claudia A. W., Kuijer, Martien, van Offenbeek, Jody, van Lith, Lambertus H. C. J., Smit, Martine J., Leurs, Rob, Zaman, Guido J. R., Vischer, Henry F.
Publicado em 2013

Llama-derived Single Variable Domains (Nanobodies) Directed against Chemokine Receptor CXCR7 Reduce Head and Neck Cancer Cell Growth in Vivo

Por Maussang, David, Mujić-Delić, Azra, Descamps, Francis J., Stortelers, Catelijne, Vanlandschoot, Peter, Stigter-van Walsum, Marijke, Vischer, Henry F., van Roy, Maarten, Vosjan, Maria, Gonzalez-Pajuelo, Maria, van Dongen, Guus A. M. S., Merchiers, Pascal, van Rompaey, Philippe, Smit, Martine J.
Publicado em 2013

The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice

Por Bongers, Gerold, Maussang, David, Muniz, Luciana R., Noriega, Vanessa M., Fraile-Ramos, Alberto, Barker, Nick, Marchesi, Federica, Thirunarayanan, Nanthakumar, Vischer, Henry F., Qin, Lihui, Mayer, Lloyd, Harpaz, Noam, Leurs, Rob, Furtado, Glaucia C., Clevers, Hans, Tortorella, Domenico, Smit, Martine J., Lira, Sergio A.
Publicado em 2010

Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H(4) and the ion channel serotonin 5-HT(3A)

Por Verheij, Mark H.P., de Graaf, Chris, de Kloe, Gerdien E., Nijmeijer, Saskia, Vischer, Henry F., Smits, Rogier A., Zuiderveld, Obbe P., Hulscher, Saskia, Silvestri, Linda, Thompson, Andrew J., van Muijlwijk-Koezen, Jacqueline E., Lummis, Sarah C.R., Leurs, Rob, de Esch, Iwan J.P.
Publicado em 2011

Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology

Por Hauwert, Niels J., Mocking, Tamara A. M., Da Costa Pereira, Daniel, Kooistra, Albert J., Wijnen, Lisa M., Vreeker, Gerda C. M., Verweij, Eléonore W. E., De Boer, Albertus H., Smit, Martine J., De Graaf, Chris, Vischer, Henry F., de Esch, Iwan J. P., Wijtmans, Maikel, Leurs, Rob
Publicado no J Am Chem Soc (2018)

Chemokine cooperativity is caused by competitive glycosaminoglycan binding

Por Verkaar, Folkert, van Offenbeek, Jody, van der Lee, Miranda M.C., van Lith, Lambertus H.C.J., Watts, Anne O., Rops, Angelique L.W.M.M., Aguilar, David C., Ziarek, Joshua J., van der Vlag, Johan, Handel, Tracy M., Volkman, Brian F., Proudfoot, Amanda E.I., Vischer, Henry F., Zaman, Guido J.R., Smit, Martine J.
Publicado em 2014

The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth

Por Heukers, Raimond, Fan, Tian Shu, de Wit, Raymond H., van Senten, Jeffrey R., De Groof, Timo W. M., Bebelman, Maarten P., Lagerweij, Tonny, Vieira, Joao, de Munnik, Sabrina M., Smits-de Vries, Laura, van Offenbeek, Jody, Rahbar, Afsar, van Hoorick, Diane, Söderberg-Naucler, Cecilia, Würdinger, Thomas, Leurs, Rob, Siderius, Marco, Vischer, Henry F., Smit, Martine J.
Publicado no Oncogene (2018)