The Target Residence Time of Antihistamines Determines Their Antagonism of the G Protein-Coupled Histamine H1 Receptor

Por Bosma, Reggie, Witt, Gesa, Vaas, Lea A. I., Josimovic, Ivana, Gribbon, Philip, Vischer, Henry F., Gul, Sheraz, Leurs, Rob
Publicado no Front Pharmacol (2017)

Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

Por Linciano, Pasquale, Dawson, Alice, Pöhner, Ina, Costa, David M., Sá, Monica S., Cordeiro-da-Silva, Anabela, Luciani, Rosaria, Gul, Sheraz, Witt, Gesa, Ellinger, Bernhard, Kuzikov, Maria, Gribbon, Philip, Reinshagen, Jeanette, Wolf, Markus, Behrens, Birte, Hannaert, Véronique, Michels, Paul A. M., Nerini, Erika, Pozzi, Cecilia, di Pisa, Flavio, Landi, Giacomo, Santarem, Nuno, Ferrari, Stefania, Saxena, Puneet, Lazzari, Sandra, Cannazza, Giuseppe, Freitas-Junior, Lucio H., Moraes, Carolina B., Pascoalino, Bruno S., Alcântara, Laura M., Bertolacini, Claudia P., Fontana, Vanessa, Wittig, Ulrike, Müller, Wolfgang, Wade, Rebecca C., Hunter, William N., Mangani, Stefano, Costantino, Luca, Costi, Maria P.
Publicado no ACS Omega (2017)