Constitutive ß-Catenin Signaling by the Viral Chemokine Receptor US28

Chronic activation of Wnt/ß-catenin signaling is found in a variety of human malignancies including melanoma, colorectal and hepatocellular carcinomas. Interestingly, expression of the HCMV-encoded chemokine receptor US28 in intestinal epithelial cells promotes intestinal neoplasia in transgenic mic...

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Detalhes bibliográficos
Main Authors: Langemeijer, Ellen V., Slinger, Erik, de Munnik, Sabrina, Schreiber, Andreas, Maussang, David, Vischer, Henry, Verkaar, Folkert, Leurs, Rob, Siderius, Marco, Smit, Martine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493591/
https://ncbi.nlm.nih.gov/pubmed/23145028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048935
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