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A Photoswitchable Agonist for the Histamine H(3) Receptor, a Prototypic Family A G‐Protein‐Coupled Receptor
Spatiotemporal control over biochemical signaling processes involving G protein‐coupled receptors (GPCRs) is highly desired for dissecting their complex intracellular signaling. We developed sixteen photoswitchable ligands for the human histamine H(3) receptor (hH(3)R). Upon illumination, key compou...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6563694/ https://ncbi.nlm.nih.gov/pubmed/30735597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201813110 |
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