Cancer epigenetics drug discovery and development: the challenge of hitting the mark

द्वारा Campbell, Robert M., Tummino, Peter J.
प्रकाशित 2014

Cancer epigenetics drug discovery and development: the challenge of hitting the mark

द्वारा Campbell, Robert M., Tummino, Peter J.
प्रकाशित 2014

Characterization of an exosite binding inhibitor of matrix metalloproteinase 13

द्वारा Gooljarsingh, Lata T., Lakdawala, Ami, Coppo, Frank, Luo, Lusong, Fields, Gregg B., Tummino, Peter J., Gontarek, Richard R.
प्रकाशित 2008

ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches

द्वारा Li, Hua, Bitler, Benjamin G., Vathipadiekal, Vinod, Maradeo, Marie E., Slifker, Michael, Creasy, Caretha L., Tummino, Peter J., Cairns, Paul, Birrer, Michael J., Zhang, Rugang
प्रकाशित 2011

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer

द्वारा Wyce, Anastasia, Degenhardt, Yan, Bai, Yuchen, Le, BaoChau, Korenchuk, Susan, Crouthamel, Ming-Chih, McHugh, Charles F., Vessella, Robert, Creasy, Caretha L., Tummino, Peter J., Barbash, Olena
प्रकाशित 2013

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues

द्वारा Gooljarsingh, Lata T., Fernandes, Christine, Yan, Kang, Zhang, Hong, Grooms, Michael, Johanson, Kyung, Sinnamon, Robert H., Kirkpatrick, Robert B., Kerrigan, John, Lewis, Tia, Arnone, Marc, King, Alastair J., Lai, Zhihong, Copeland, Robert A., Tummino, Peter J.
प्रकाशित 2006

Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation

द्वारा Van Aller, Glenn S., Reynoird, Nicolas, Barbash, Olena, Huddleston, Michael, Liu, Shichong, Zmoos, Anne-Flore, McDevitt, Patrick, Sinnamon, Robert, Le, BaoChau, Mas, Gloria, Annan, Roland, Sage, Julien, Garcia, Benjamin A., Tummino, Peter J., Gozani, Or, Kruger, Ryan G.
प्रकाशित 2012

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

द्वारा Mazur, Pawel K., Reynoird, Nicolas, Khatri, Purvesh, Jansen, Pascal W.T.C., Wilkinson, Alex, Liu, Shichong, Barbash, Olena, Van Aller, Glenn S., Huddleston, Michael, Dhanak, Dashyant, Tummino, Peter J., Kruger, Ryan G., Garcia, Benjamin, Butte, Atul J., Vermeulen, Michiel, Sage, Julien, Gozani, Or
प्रकाशित 2014

MEK inhibitors overcome resistance to BET inhibition across a number of solid and hematologic cancers

द्वारा Wyce, Anastasia, Matteo, Jeanne J., Foley, Shawn W., Felitsky, Daniel J., Rajapurkar, Satyajit R., Zhang, Xi-Ping, Musso, Melissa C., Korenchuk, Susan, Karpinich, Natalie O., Keenan, Kathryn M., Stern, Melissa, Mathew, Lijoy K., McHugh, Charles F., McCabe, Michael T., Tummino, Peter J., Kruger, Ryan G., Carpenter, Christopher, Barbash, Olena
में प्रकाशित Oncogenesis (2018)

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

द्वारा Wyce, Anastasia, Ganji, Gopinath, Smitheman, Kimberly N., Chung, Chun-wa, Korenchuk, Susan, Bai, Yuchen, Barbash, Olena, Le, BaoChau, Craggs, Peter D., McCabe, Michael T., Kennedy-Wilson, Karen M., Sanchez, Lydia V., Gosmini, Romain L., Parr, Nigel, McHugh, Charles F., Dhanak, Dashyant, Prinjha, Rab K., Auger, Kurt R., Tummino, Peter J.
प्रकाशित 2013

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

द्वारा McCabe, Michael T., Graves, Alan P., Ganji, Gopinath, Diaz, Elsie, Halsey, Wendy S., Jiang, Yong, Smitheman, Kimberly N., Ott, Heidi M., Pappalardi, Melissa B., Allen, Kimberly E., Chen, Stephanie B., Della Pietra, Anthony, Dul, Edward, Hughes, Ashley M., Gilbert, Seth A., Thrall, Sara H., Tummino, Peter J., Kruger, Ryan G., Brandt, Martin, Schwartz, Benjamin, Creasy, Caretha L.
प्रकाशित 2012

Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2

द्वारा Verma, Sharad K., Tian, Xinrong, LaFrance, Louis V., Duquenne, Céline, Suarez, Dominic P., Newlander, Kenneth A., Romeril, Stuart P., Burgess, Joelle L., Grant, Seth W., Brackley, James A., Graves, Alan P., Scherzer, Daryl A., Shu, Art, Thompson, Christine, Ott, Heidi M., Aller, Glenn S. Van, Machutta, Carl A., Diaz, Elsie, Jiang, Yong, Johnson, Neil W., Knight, Steven D., Kruger, Ryan G., McCabe, Michael T., Dhanak, Dashyant, Tummino, Peter J., Creasy, Caretha L., Miller, William H.
प्रकाशित 2012

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

द्वारा Knight, Steven D., Adams, Nicholas D., Burgess, Joelle L., Chaudhari, Amita M., Darcy, Michael G., Donatelli, Carla A., Luengo, Juan I., Newlander, Ken A., Parrish, Cynthia A., Ridgers, Lance H., Sarpong, Martha A., Schmidt, Stanley J., Van Aller, Glenn S., Carson, Jeffrey D., Diamond, Melody A., Elkins, Patricia A., Gardiner, Christine M., Garver, Eric, Gilbert, Seth A., Gontarek, Richard R., Jackson, Jeffrey R., Kershner, Kevin L., Luo, Lusong, Raha, Kaushik, Sherk, Christian S., Sung, Chiu-Mei, Sutton, David, Tummino, Peter J., Wegrzyn, Ronald J., Auger, Kurt R., Dhanak, Dashyant
प्रकाशित 2010