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Cancer epigenetics drug discovery and development: the challenge of hitting the mark

Over the past several years, there has been rapidly expanding evidence of epigenetic dysregulation in cancer, in which histone and DNA modification play a critical role in tumor growth and survival. These findings have gained the attention of the drug discovery and development community, and offer t...

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Detalhes bibliográficos
Main Authors: Campbell, Robert M., Tummino, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871251/
https://ncbi.nlm.nih.gov/pubmed/24382391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71605
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