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Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation
Smyd3 is a lysine methyltransferase implicated in chromatin and cancer regulation. Here we show that Smyd3 catalyzes histone H4 methylation at lysine 5 (H4K5me). This novel histone methylation mark is detected in diverse cell types and its formation is attenuated by depletion of Smyd3 protein. Furth...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368817/ https://ncbi.nlm.nih.gov/pubmed/22419068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19506 |
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