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Methylation of the Retinoblastoma Tumor Suppressor by SMYD2

The retinoblastoma tumor suppressor (RB) is a central cell cycle regulator and tumor suppressor. RB cellular functions are known to be regulated by a diversity of post-translational modifications such as phosphorylation and acetylation, raising the possibility that RB may also be methylated in cells...

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Autores principales: Saddic, Louis A., West, Lisandra E., Aslanian, Aaron, Yates, John R., Rubin, Seth M., Gozani, Or, Sage, Julien
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988378/
https://ncbi.nlm.nih.gov/pubmed/20870719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.137612
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