Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36

Por Poulin, Myles B., Schneck, Jessica L., Matico, Rosalie E., McDevitt, Patrick J., Huddleston, Michael J., Hou, Wangfang, Johnson, Neil W., Thrall, Sara H., Meek, Thomas D., Schramm, Vern L.
Publicado no Proc Natl Acad Sci U S A (2016)

Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation

Por Van Aller, Glenn S., Reynoird, Nicolas, Barbash, Olena, Huddleston, Michael, Liu, Shichong, Zmoos, Anne-Flore, McDevitt, Patrick, Sinnamon, Robert, Le, BaoChau, Mas, Gloria, Annan, Roland, Sage, Julien, Garcia, Benjamin A., Tummino, Peter J., Gozani, Or, Kruger, Ryan G.
Publicado em 2012

Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors

Por Qiu, Xiayang, Janson, Cheryl A., Smith, Ward W., Green, Susan M., McDevitt, Patrick, Johanson, Kyung, Carter, Paul, Hibbs, Martin, Lewis, Ceri, Chalker, Alison, Fosberry, Andrew, Lalonde, Judith, Berge, John, Brown, Pamela, Houge-Frydrych, Catherine S.V., Jarvest, Richard L.
Publicado em 2001

Structures of Human DPP7 Reveal the Molecular Basis of Specific Inhibition and the Architectural Diversity of Proline-Specific Peptidases

Por Bezerra, Gustavo Arruda, Dobrovetsky, Elena, Dong, Aiping, Seitova, Almagul, Crombett, Lissete, Shewchuk, Lisa M., Hassell, Annie M., Sweitzer, Sharon M., Sweitzer, Thomas D., McDevitt, Patrick J., Johanson, Kyung O., Kennedy-Wilson, Karen M., Cossar, Doug, Bochkarev, Alexey, Gruber, Karl, Dhe-Paganon, Sirano
Publicado em 2012

Discovery of Novel Cyanamide-Based Inhibitors of Cathepsin C

Por Lainé, Dramane, Palovich, Michael, McCleland, Brent, Petitjean, Emilie, Delhom, Isabelle, Xie, Haibo, Deng, Jianghe, Lin, Guoliang, Davis, Roderick, Jolit, Anais, Nevins, Neysa, Zhao, Baoguang, Villa, Jim, Schneck, Jessica, McDevitt, Patrick, Midgett, Robert, Kmett, Casey, Umbrecht, Sandra, Peck, Brian, Davis, Alicia Bacon, Bettoun, David
Publicado em 2010

Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors

Por Lin, Hong, Zeng, Jin, Xie, Ren, Schulz, Mark J., Tedesco, Rosanna, Qu, Junya, Erhard, Karl F., Mack, James F., Raha, Kaushik, Rendina, Alan R., Szewczuk, Lawrence M., Kratz, Patricia M., Jurewicz, Anthony J., Cecconie, Ted, Martens, Stan, McDevitt, Patrick J., Martin, John D., Chen, Stephenie B., Jiang, Yong, Nickels, Leng, Schwartz, Benjamin J., Smallwood, Angela, Zhao, Baoguang, Campobasso, Nino, Qian, Yanqiu, Briand, Jacques, Rominger, Cynthia M., Oleykowski, Catherine, Hardwicke, Mary Ann, Luengo, Juan I.
Publicado no ACS Med Chem Lett (2015)