Загрузка...
Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer
BET (bromodomain and extra-terminal) proteins regulate gene expression through their ability to bind to acetylated chromatin and subsequently activate RNA PolII-driven transcriptional elongation. Small molecule BET inhibitors prevent binding of BET proteins to acetylated histones and inhibit transcr...
Сохранить в:
| Главные авторы: | , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2013
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926837/ https://ncbi.nlm.nih.gov/pubmed/24293458 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|