Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery

Bằng Brown, James R, Auger, Kurt R
Được phát hành 2011

Differentiation of Hdm2-mediated p53 ubiquitination and Hdm2 autoubiquitination activity by small molecular weight inhibitors

Bằng Lai, Zhihong, Yang, Tao, Kim, Young B., Sielecki, Thais M., Diamond, Melody A., Strack, Peter, Rolfe, Mark, Caligiuri, Maureen, Benfield, Pamela A., Auger, Kurt R., Copeland, Robert A.
Được phát hành 2002

A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours

Bằng Mak, Gabriel, Soria, Jean-Charles, Blagden, Sarah P., Plummer, Ruth, Fleming, Ronald A., Nebot, Noelia, Zhang, Jianping, Mazumdar, Jolly, Rogan, Debra, Gazzah, Anas, Rizzuto, Ivana, Greystoke, Alastair, Yan, Li, Tolson, Jerry, Auger, Kurt R., Arkenau, Hendrik-Tobias
Xuất bản năm Br J Cancer (2019)

A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [(11)C]GSK2256098

Bằng Brown, Nicholas F, Williams, Matthew, Arkenau, Hendrik-Tobias, Fleming, Ronald A, Tolson, Jerry, Yan, Li, Zhang, Jianping, Singh, Rajendra, Auger, Kurt R, Lenox, Laurie, Cox, David, Lewis, Yvonne, Plisson, Christophe, Searle, Graham, Saleem, Azeem, Blagden, Sarah, Mulholland, Paul
Xuất bản năm Neuro Oncol (2018)

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

Bằng Wyce, Anastasia, Ganji, Gopinath, Smitheman, Kimberly N., Chung, Chun-wa, Korenchuk, Susan, Bai, Yuchen, Barbash, Olena, Le, BaoChau, Craggs, Peter D., McCabe, Michael T., Kennedy-Wilson, Karen M., Sanchez, Lydia V., Gosmini, Romain L., Parr, Nigel, McHugh, Charles F., Dhanak, Dashyant, Prinjha, Rab K., Auger, Kurt R., Tummino, Peter J.
Được phát hành 2013

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)

Bằng Yang, Hongfang, Medeiros, Patricia F., Raha, Kaushik, Elkins, Patricia, Lind, Kenneth E., Lehr, Ruth, Adams, Nicholas D., Burgess, Joelle L., Schmidt, Stanley J., Knight, Steven D., Auger, Kurt R., Schaber, Michael D., Franklin, G. Joseph, Ding, Yun, DeLorey, Jennifer L., Centrella, Paolo A., Mataruse, Sibongile, Skinner, Steven R., Clark, Matthew A., Cuozzo, John W., Evindar, Ghotas
Xuất bản năm ACS Med Chem Lett (2015)

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Bằng Dawson, Mark A., Prinjha, Rab K., Dittman, Antje, Giotopoulos, George, Bantscheff, Marcus, Chan, Wai-In, Robson, Samuel C, Chung, Chun-wa, Hopf, Carsten, Savitski, Mikhail M., Huthmacher, Carola, Gudgin, Emma, Lugo, Dave, Beinke, Soren, Chapman, Trevor D., Roberts, Emma J., Soden, Peter E, Auger, Kurt R., Mirguet, Olivier, Doehner, Konstanze, Delwel, Ruud, Burnett, Alan K., Jeffrey, Phillip, Drewes, Gerard, Lee, Kevin, Huntly, Brian J.P, Kouzarides, Tony
Được phát hành 2011

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Bằng Knight, Steven D., Adams, Nicholas D., Burgess, Joelle L., Chaudhari, Amita M., Darcy, Michael G., Donatelli, Carla A., Luengo, Juan I., Newlander, Ken A., Parrish, Cynthia A., Ridgers, Lance H., Sarpong, Martha A., Schmidt, Stanley J., Van Aller, Glenn S., Carson, Jeffrey D., Diamond, Melody A., Elkins, Patricia A., Gardiner, Christine M., Garver, Eric, Gilbert, Seth A., Gontarek, Richard R., Jackson, Jeffrey R., Kershner, Kevin L., Luo, Lusong, Raha, Kaushik, Sherk, Christian S., Sung, Chiu-Mei, Sutton, David, Tummino, Peter J., Wegrzyn, Ronald J., Auger, Kurt R., Dhanak, Dashyant
Được phát hành 2010

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295

Bằng Qian, Xiangping, McDonald, Andrew, Zhou, Han-Jie, Adams, Nicholas D., Parrish, Cynthia A., Duffy, Kevin J., Fitch, Duke M., Tedesco, Rosanna, Ashcraft, Luke W., Yao, Bing, Jiang, Hong, Huang, Jennifer K., Marin, Melchor V., Aroyan, Carrie E., Wang, Jianchao, Ahmed, Seyed, Burgess, Joelle L., Chaudhari, Amita M., Donatelli, Carla A., Darcy, Michael G., Ridgers, Lance H., Newlander, Ken A., Schmidt, Stanley J., Chai, Deping, Colón, Mariela, Zimmerman, Michael N., Lad, Latesh, Sakowicz, Roman, Schauer, Stephen, Belmont, Lisa, Baliga, Ramesh, Pierce, Daniel W., Finer, Jeffrey T., Wang, Zhengping, Morgan, Bradley P., Morgans, David J., Auger, Kurt R., Sung, Chiu-Mei, Carson, Jeff D., Luo, Lusong, Hugger, Erin D., Copeland, Robert A., Sutton, David, Elliott, John D., Jackson, Jeffrey R., Wood, Kenneth W., Dhanak, Dashyant, Bergnes, Gustave, Knight, Steven D.
Được phát hành 2010