Sentinel lymph node biopsy: Not yet standard of care for melanoma

Por Thomas, J Meirion, Clark, Matthew A
Publicado em 2004

Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags

Por Litovchick, Alexander, Clark, Matthew A, Keefe, Anthony D
Publicado em 2014

An extensible interface for QM/MM molecular dynamics simulations with AMBER

Por Götz, Andreas W., Clark, Matthew A., Walker, Ross C.
Publicado em 2013

Electronic Absorption Spectra from MM and ab initio QM/MM Molecular Dynamics: Environmental Effects on the Absorption Spectrum of Photoactive Yellow Protein

Por Isborn, Christine M., Götz, Andreas W., Clark, Matthew A., Walker, Ross C., Martínez, Todd J.
Publicado em 2012

Fast Motions of Key Methyl Groups in Amyloid-β Fibrils

Por Vugmeyster, Liliya, Ostrovsky, Dmitry, Clark, Matthew A., Falconer, Isaac B., Hoatson, Gina L., Qiang, Wei
Publicado no Biophys J (2016)

Flexibility and Solvation of Amyloid-β Hydrophobic Core

Por Vugmeyster, Liliya, Clark, Matthew A., Falconer, Isaac B., Ostrovsky, Dmitry, Gantz, Donald, Qiang, Wei, Hoatson, Gina L.
Publicado no J Biol Chem (2016)

The unusual internal motion of the villin headpiece subdomain

Por Harpole, Kyle W., O'Brien, Evan S., Clark, Matthew A., McKnight, C. James, Vugmeyster, Liliya, Wand, A. Joshua
Publicado no Protein Sci (2015)

Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library

Por Litovchick, Alexander, Dumelin, Christoph E., Habeshian, Sevan, Gikunju, Diana, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Sigel, Eric A., Cuozzo, John W., Keefe, Anthony D., Clark, Matthew A.
Publicado no Sci Rep (2015)

Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT)

Por Ding, Yun, O’Keefe, Heather, DeLorey, Jennifer L., Israel, David I., Messer, Jeffrey A., Chiu, Cynthia H., Skinner, Steven R., Matico, Rosalie E., Murray-Thompson, Monique F., Li, Fan, Clark, Matthew A., Cuozzo, John W., Arico-Muendel, Christopher, Morgan, Barry A.
Publicado no ACS Med Chem Lett (2015)

Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology

Por Soutter, Holly H., Centrella, Paolo, Clark, Matthew A., Cuozzo, John W., Dumelin, Christoph E., Guie, Marie-Aude, Habeshian, Sevan, Keefe, Anthony D., Kennedy, Kaitlyn M., Sigel, Eric A., Troast, Dawn M., Zhang, Ying, Ferguson, Andrew D., Davies, Gareth, Stead, Eleanor R., Breed, Jason, Madhavapeddi, Prashanti, Read, Jon A.
Publicado no Proc Natl Acad Sci U S A (2016)

Discovery of a Potent Class of PI3Kα Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT)

Por Yang, Hongfang, Medeiros, Patricia F., Raha, Kaushik, Elkins, Patricia, Lind, Kenneth E., Lehr, Ruth, Adams, Nicholas D., Burgess, Joelle L., Schmidt, Stanley J., Knight, Steven D., Auger, Kurt R., Schaber, Michael D., Franklin, G. Joseph, Ding, Yun, DeLorey, Jennifer L., Centrella, Paolo A., Mataruse, Sibongile, Skinner, Steven R., Clark, Matthew A., Cuozzo, John W., Evindar, Ghotas
Publicado no ACS Med Chem Lett (2015)

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

Por Deng, Hongfeng, Zhou, Jingye, Sundersingh, Flora S., Summerfield, Jennifer, Somers, Don, Messer, Jeffrey A., Satz, Alexander L., Ancellin, Nicolas, Arico-Muendel, Christopher C., (Sargent) Bedard, Katie L., Beljean, Arthur, Belyanskaya, Svetlana L., Bingham, Ryan, Smith, Sarah E., Boursier, Eric, Carter, Paul, Centrella, Paolo A., Clark, Matthew A., Chung, Chun-wa, Davie, Christopher P., Delorey, Jennifer L., Ding, Yun, Franklin, G. Joseph, Grady, LaShadric C., Herry, Kenny, Hobbs, Clare, Kollmann, Christopher S., Morgan, Barry A., (Pothier) Kaushansky, Laura J., Zhou, Quan
Publicado no ACS Med Chem Lett (2015)

Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors

Por Johannes, Jeffrey W., Bates, Stephanie, Beigie, Carl, Belmonte, Matthew A., Breen, John, Cao, Shenggen, Centrella, Paolo A., Clark, Matthew A., Cuozzo, John W., Dumelin, Christoph E., Ferguson, Andrew D., Habeshian, Sevan, Hargreaves, David, Joubran, Camil, Kazmirski, Steven, Keefe, Anthony D., Lamb, Michelle L., Lan, Haiye, Li, Yunxia, Ma, Hao, Mlynarski, Scott, Packer, Martin J., Rawlins, Philip B., Robbins, Daniel W., Shen, Haidong, Sigel, Eric A., Soutter, Holly H., Su, Nancy, Troast, Dawn M., Wang, Haiyun, Wickson, Kate F., Wu, Chengyan, Zhang, Ying, Zhao, Qiuying, Zheng, Xiaolan, Hird, Alexander W.
Publicado no ACS Med Chem Lett (2016)