Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology

Por Johannes, Jeffrey W., Almeida, Lynsie, Barlaam, Bernard, Boriack-Sjodin, P. Ann, Casella, Robert, Croft, Rosemary A., Dishington, Allan P., Gingipalli, Lakshmaiah, Gu, Chungang, Hawkins, Janet L., Holmes, Jane L., Howard, Tina, Huang, Jian, Ioannidis, Stephanos, Kazmirski, Steven, Lamb, Michelle L., McGuire, Thomas M., Moore, Jane E., Ogg, Derek, Patel, Anil, Pike, Kurt G., Pontz, Timothy, Robb, Graeme R., Su, Nancy, Wang, Haiyun, Wu, Xiaoyun, Zhang, Hai-Jun, Zhang, Yue, Zheng, Xiaolan, Wang, Tao
Publicado no ACS Med Chem Lett (2015)

Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors

Por Johannes, Jeffrey W., Bates, Stephanie, Beigie, Carl, Belmonte, Matthew A., Breen, John, Cao, Shenggen, Centrella, Paolo A., Clark, Matthew A., Cuozzo, John W., Dumelin, Christoph E., Ferguson, Andrew D., Habeshian, Sevan, Hargreaves, David, Joubran, Camil, Kazmirski, Steven, Keefe, Anthony D., Lamb, Michelle L., Lan, Haiye, Li, Yunxia, Ma, Hao, Mlynarski, Scott, Packer, Martin J., Rawlins, Philip B., Robbins, Daniel W., Shen, Haidong, Sigel, Eric A., Soutter, Holly H., Su, Nancy, Troast, Dawn M., Wang, Haiyun, Wickson, Kate F., Wu, Chengyan, Zhang, Ying, Zhao, Qiuying, Zheng, Xiaolan, Hird, Alexander W.
Publicado no ACS Med Chem Lett (2016)