Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors

Por Barlaam, Bernard, Anderton, Judith, Ballard, Peter, Bradbury, Robert H., Hennequin, Laurent F. A., Hickinson, D. Mark, Kettle, Jason G., Kirk, George, Klinowska, Teresa, Lambert-van der Brempt, Christine, Trigwell, Cath, Vincent, John, Ogilvie, Donald
Publicado em 2013

Targeting the kinase activities of ATR and ATM exhibits therapeutic potential in a mouse model of MLL-rearranged AML

Por Morgado-Palacin, Isabel, Day, Amanda, Murga, Matilde, Lafarga, Vanesa, Anton, Marta Elena, Tubbs, Anthony, Chen, Hua Tang, Ergan, Aysegul, Anderson, Rhonda, Bhandoola, Avinash, Pike, Kurt G., Barlaam, Bernard, Cadogan, Elaine, Wang, Xi, Pierce, Andrew J., Hubbard, Chad, Armstrong, Scott A., Nussenzweig, André, Fernandez-Capetillo, Oscar
Publicado no Sci Signal (2016)

Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology

Por Johannes, Jeffrey W., Almeida, Lynsie, Barlaam, Bernard, Boriack-Sjodin, P. Ann, Casella, Robert, Croft, Rosemary A., Dishington, Allan P., Gingipalli, Lakshmaiah, Gu, Chungang, Hawkins, Janet L., Holmes, Jane L., Howard, Tina, Huang, Jian, Ioannidis, Stephanos, Kazmirski, Steven, Lamb, Michelle L., McGuire, Thomas M., Moore, Jane E., Ogg, Derek, Patel, Anil, Pike, Kurt G., Pontz, Timothy, Robb, Graeme R., Su, Nancy, Wang, Haiyun, Wu, Xiaoyun, Zhang, Hai-Jun, Zhang, Yue, Zheng, Xiaolan, Wang, Tao
Publicado no ACS Med Chem Lett (2015)