Fast Motions of Key Methyl Groups in Amyloid-β Fibrils

Amyloid-β (Aβ) peptide is the major component of plaques found in Alzheimer’s disease patients. Using solid-state (2)H NMR relaxation performed on selectively deuterated methyl groups, we probed the dynamics in the threefold symmetric and twofold symmetric polymorphs of native Aβ as well as the prot...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Vugmeyster, Liliya, Ostrovsky, Dmitry, Clark, Matthew A., Falconer, Isaac B., Hoatson, Gina L., Qiang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2016
Assuntos:
Proteins
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113154/
https://ncbi.nlm.nih.gov/pubmed/27851938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.001
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares