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Fast Motions of Key Methyl Groups in Amyloid-β Fibrils
Amyloid-β (Aβ) peptide is the major component of plaques found in Alzheimer’s disease patients. Using solid-state (2)H NMR relaxation performed on selectively deuterated methyl groups, we probed the dynamics in the threefold symmetric and twofold symmetric polymorphs of native Aβ as well as the prot...
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| Publié dans: | Biophys J |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5113154/ https://ncbi.nlm.nih.gov/pubmed/27851938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.001 |
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