Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia

Por Gallipoli, Paolo, Giotopoulos, George, Huntly, Brian J.P.
Publicado no Ther Adv Hematol (2015)

Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development

Por Barrett, Neil A., Malouf, Camille, Kapeni, Chrysa, Bacon, Wendi A., Giotopoulos, George, Jacobsen, Sten Eirik W., Huntly, Brian J., Ottersbach, Katrin
Publicado no Cell Rep (2016)

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/−) leukemia

Por van der Weyden, Louise, Giotopoulos, George, Wong, Kim, Rust, Alistair G., Robles-Espinoza, Carla Daniela, Osaki, Hikari, Huntly, Brian J., Adams, David J.
Publicado no BMC Cancer (2015)

Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice

Por van der Weyden, Louise, Giotopoulos, George, Rust, Alistair G., Matheson, Louise S., van Delft, Frederik W., Kong, Jun, Corcoran, Anne E., Greaves, Mel F., Mullighan, Charles G., Huntly, Brian J., Adams, David J.
Publicado em 2011

A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

Por Giotopoulos, George, van der Weyden, Louise, Osaki, Hikari, Rust, Alistair G., Gallipoli, Paolo, Meduri, Eshwar, Horton, Sarah J., Chan, Wai-In, Foster, Donna, Prinjha, Rab K., Pimanda, John E., Tenen, Daniel G., Vassiliou, George S., Koschmieder, Steffen, Adams, David J., Huntly, Brian J.P.
Publicado no J Exp Med (2015)

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Por Dawson, Mark A., Prinjha, Rab K., Dittman, Antje, Giotopoulos, George, Bantscheff, Marcus, Chan, Wai-In, Robson, Samuel C, Chung, Chun-wa, Hopf, Carsten, Savitski, Mikhail M., Huthmacher, Carola, Gudgin, Emma, Lugo, Dave, Beinke, Soren, Chapman, Trevor D., Roberts, Emma J., Soden, Peter E, Auger, Kurt R., Mirguet, Olivier, Doehner, Konstanze, Delwel, Ruud, Burnett, Alan K., Jeffrey, Phillip, Drewes, Gerard, Lee, Kevin, Huntly, Brian J.P, Kouzarides, Tony
Publicado em 2011