Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development

MLL-AF4+ infant B cell acute lymphoblastic leukemia is characterized by an early onset and dismal survival. It initiates before birth, and very little is known about the early stages of the disease’s development. Using a conditional Mll-AF4-expressing mouse model in which fusion expression is target...

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Publicado no:Cell Rep
Main Authors: Barrett, Neil A., Malouf, Camille, Kapeni, Chrysa, Bacon, Wendi A., Giotopoulos, George, Jacobsen, Sten Eirik W., Huntly, Brian J., Ottersbach, Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967476/
https://ncbi.nlm.nih.gov/pubmed/27396339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.06.046
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