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The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment
Chromosome rearrangements involving the mixed-lineage leukemia gene (MLL) create MLL-fusion proteins, which could drive both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). The lineage decision of MLL-fusion leukemia is influenced by the fusion partner and microenvironment. To i...
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| Publicado no: | Blood |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561902/ https://ncbi.nlm.nih.gov/pubmed/28637661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-04-777185 |
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