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Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia

Acute myeloid leukemia (AML), the most prevalent acute leukemia in adults, is an aggressive hematological malignancy arising in hematopoietic stem and progenitor cells. With the exception of a few specific AML subtypes, the mainstays of treatment have not significantly changed over the last 20 years...

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Détails bibliographiques
Publié dans:Ther Adv Hematol
Auteurs principaux: Gallipoli, Paolo, Giotopoulos, George, Huntly, Brian J.P.
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480521/
https://ncbi.nlm.nih.gov/pubmed/26137202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715577614
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