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Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia

Acute myeloid leukemia (AML), the most prevalent acute leukemia in adults, is an aggressive hematological malignancy arising in hematopoietic stem and progenitor cells. With the exception of a few specific AML subtypes, the mainstays of treatment have not significantly changed over the last 20 years...

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Bibliographic Details
Published in:Ther Adv Hematol
Main Authors: Gallipoli, Paolo, Giotopoulos, George, Huntly, Brian J.P.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480521/
https://ncbi.nlm.nih.gov/pubmed/26137202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715577614
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