The Role of Metabolism in the Development of Personalized Therapies in Acute Myeloid Leukemia

Yazar: Dembitz, Vilma, Gallipoli, Paolo
Yayımlandı Front Oncol (2021)

Prognostic models turn the Heat(IT)up on FLT3(ITD)-mutated AML

Yazar: Gallipoli, Paolo, Huntly, Brian J.P.
Yayımlandı Clin Cancer Res (2018)

Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia

Yazar: Gallipoli, Paolo, Giotopoulos, George, Huntly, Brian J.P.
Yayımlandı Ther Adv Hematol (2015)

High Prevalence of Heparin Induced Thrombocytopenia with Thrombosis Among Patients with Essential Thrombocytemia Carrying V617F Mutation

Yazar: Castelli, Roberto, Gallipoli, Paolo, Schiavon, Riccardo, Teatini, Thomas, Deliliers, Giorgio Lambertenghi, Bergamaschini, Luigi
Yayımlandı J Thromb Thrombolysis (2018)

The UK SPIRIT 1 trial in newly-diagnosed chronic myeloid leukaemia (CML)

Yazar: Gallipoli, Paolo, Clark, Richard E, Byrne, Jenny, Apperley, Jane F, Milojkovic, Dragana, Foroni, Letizia, Goldman, John M, O’Brien, Stephen
Yayımlandı Br J Haematol (2022)

Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation

Yazar: Gallipoli, Paolo, Pellicano, Francesca, Morrison, Heather, Laidlaw, Kamilla, Allan, Elaine K., Bhatia, Ravi, Copland, Mhairi, Jørgensen, Heather G., Holyoake, Tessa L.
Baskı/Yayın Bilgisi 2013

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34(+) cells in vitro and in vivo

Yazar: Gallipoli, Paolo, Cook, Amy, Rhodes, Susan, Hopcroft, Lisa, Wheadon, Helen, Whetton, Anthony D., Jørgensen, Heather G., Bhatia, Ravi, Holyoake, Tessa L.
Baskı/Yayın Bilgisi 2014

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression

Yazar: Tarafdar, Anuradha, Hopcroft, Lisa E. M., Gallipoli, Paolo, Pellicano, Francesca, Cassels, Jennifer, Hair, Alan, Korfi, Koorosh, Jørgensen, Heather G., Vetrie, David, Holyoake, Tessa L., Michie, Alison M.
Yayımlandı Blood (2017)

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Yazar: Sasca, Daniel, Yun, Haiyang, Giotopoulos, George, Szybinski, Jakub, Evan, Theo, Wilson, Nicola K., Gerstung, Moritz, Gallipoli, Paolo, Green, Anthony R., Hills, Robert, Russell, Nigel, Osborne, Cameron S., Papaemmanuil, Elli, Göttgens, Berthold, Campbell, Peter, Huntly, Brian J. P.
Yayımlandı Blood (2019)

Epigenetic reprogramming sensitizes CML stem cells to combined EZH2 and tyrosine kinase inhibition

Yazar: Scott, Mary T., Korfi, Koorosh, Saffrey, Peter, Hopcroft, Lisa E.M., Kinstrie, Ross, Pellicano, Francesca, Guenther, Carla, Gallipoli, Paolo, Cruz, Michelle, Dunn, Karen, Jorgensen, Heather G., Cassels, Jennifer E., Hamilton, Ashley, Crossan, Andrew, Sinclair, Amy, Holyoake, Tessa L., Vetrie, David
Yayımlandı Cancer Discov (2016)

Glutaminolysis is a metabolic dependency in FLT3(ITD) acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition

Yazar: Gallipoli, Paolo, Giotopoulos, George, Tzelepis, Konstantinos, Costa, Ana S.H., Vohra, Shabana, Medina-Perez, Paula, Basheer, Faisal, Marando, Ludovica, Di Lisio, Lorena, Dias, Joao M. L., Yun, Haiyang, Sasca, Daniel, Horton, Sarah J., Vassiliou, George, Frezza, Christian, Huntly, Brian J.P.
Yayımlandı Blood (2018)

A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

Yazar: Giotopoulos, George, van der Weyden, Louise, Osaki, Hikari, Rust, Alistair G., Gallipoli, Paolo, Meduri, Eshwar, Horton, Sarah J., Chan, Wai-In, Foster, Donna, Prinjha, Rab K., Pimanda, John E., Tenen, Daniel G., Vassiliou, George S., Koschmieder, Steffen, Adams, David J., Huntly, Brian J.P.
Yayımlandı J Exp Med (2015)

Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex

Yazar: Chen, Min, Gallipoli, Paolo, DeGeer, Donna, Sloma, Ivan, Forrest, Donna L., Chan, Matthew, Lai, Damian, Jorgensen, Heather, Ringrose, Ashley, Wang, Hui Mi, Lambie, Karen, Nakamoto, Helen, Saw, Kyi Min, Turhan, Ali, Arlinghaus, Ralph, Paul, James, Stobo, Jon, Barnett, Michael J., Eaves, Allen, Eaves, Connie J, Holyoake, Tessa L., Jiang, Xiaoyan
Baskı/Yayın Bilgisi 2013

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML

Yazar: Basheer, Faisal, Giotopoulos, George, Meduri, Eshwar, Yun, Haiyang, Mazan, Milena, Sasca, Daniel, Gallipoli, Paolo, Marando, Ludovica, Gozdecka, Malgorzata, Asby, Ryan, Sheppard, Olivia, Dudek, Monika, Bullinger, Lars, Döhner, Hartmut, Dillon, Richard, Freeman, Sylvie, Ottmann, Oliver, Burnett, Alan, Russell, Nigel, Papaemmanuil, Elli, Hills, Robert, Campbell, Peter, Vassiliou, George S., Huntly, Brian J.P.
Yayımlandı J Exp Med (2019)

Mutational synergy during leukemia induction remodels chromatin accessibility, modification and 3-Dimensional DNA topology to alter gene expression

Yazar: Yun, Haiyang, Narayan, Nisha, Vohra, Shabana, Giotopoulos, George, Mupo, Annalisa, Madrigal, Pedro, Sasca, Daniel, Lara-Astiaso, David, Horton, Sarah J., Agrawal-Singh, Shuchi, Meduri, Eshwar, Basheer, Faisal, Marando, Ludovica, Gozdecka, Malgorzata, Dovey, Oliver M., Castillo-Venzor, Aracely, Wang, Xiaonan, Gallipoli, Paolo, Müller-Tidow, Carsten, Osborne, Cameron S., Vassiliou, George S., Huntly, Brian J. P.
Yayımlandı Nat Genet (2021)

Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 mutated myelodysplasia

Yazar: Mian, Syed A, Philippe, Céline, Maniati, Eleni, Protopapa, Pantelitsa, Bergot, Tiffany, Piganeau, Marion, Nemkov, Travis, Bella, Doriana Di, Morales, Valle, Finch, Andrew J, D’Alessandro, Angelo, Bianchi, Katiuscia, Wang, Jun, Gallipoli, Paolo, Kordasti, Shahram, Kubasch, Anne Sophie, Cross, Michael, Platzbecker, Uwe, Wiseman, Daniel H, Bonnet, Dominique, Bernard, Delphine G, Gribben, John G, Rouault-Pierre, Kevin
Yayımlandı Sci Transl Med (2023)

Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy

Yazar: Forte, Dorian, García-Fernández, María, Sánchez-Aguilera, Abel, Stavropoulou, Vaia, Fielding, Claire, Martín-Pérez, Daniel, López, Juan Antonio, Costa, Ana S.H., Tronci, Laura, Nikitopoulou, Efterpi, Barber, Michael, Gallipoli, Paolo, Marando, Ludovica, Fernández de Castillejo, Carlos López, Tzankov, Alexandar, Dietmann, Sabine, Cavo, Michele, Catani, Lucia, Curti, Antonio, Vázquez, Jesús, Frezza, Christian, Huntly, Brian J., Schwaller, Juerg, Méndez-Ferrer, Simón
Yayımlandı Cell Metab (2020)

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Yazar: Tzelepis, Konstantinos, Koike-Yusa, Hiroko, De Braekeleer, Etienne, Li, Yilong, Metzakopian, Emmanouil, Dovey, Oliver M., Mupo, Annalisa, Grinkevich, Vera, Li, Meng, Mazan, Milena, Gozdecka, Malgorzata, Ohnishi, Shuhei, Cooper, Jonathan, Patel, Miten, McKerrell, Thomas, Chen, Bin, Domingues, Ana Filipa, Gallipoli, Paolo, Teichmann, Sarah, Ponstingl, Hannes, McDermott, Ultan, Saez-Rodriguez, Julio, Huntly, Brian J.P., Iorio, Francesco, Pina, Cristina, Vassiliou, George S., Yusa, Kosuke
Yayımlandı Cell Rep (2016)

Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors

Yazar: Horton, Sarah J., Giotopoulos, George, Yun, Haiyang, Vohra, Shabana, Sheppard, Olivia, Bashford-Rogers, Rachael, Rashid, Mamunur, Clipson, Alexandra, Chan, Wai-In, Sasca, Daniel, Yiangou, Loukia, Osaki, Hikari, Basheer, Faisal, Gallipoli, Paolo, Burrows, Natalie, Erdem, Aysegul, Sybirna, Anastasiya, Foerster, Sarah, Zhao, Wanfeng, Sustic, Tonci, Harrison, Anna Petrunkina, Laurenti, Elisa, Okosun, Jessica, Hodson, Daniel, Wright, Penny, Smith, Ken G., Maxwell, Patrick, Fitzgibbon, Jude, Du, Ming Q., Adams, David J., Huntly, Brian J.P
Yayımlandı Nat Cell Biol (2017)

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

Yazar: Tzelepis, Konstantinos, De Braekeleer, Etienne, Aspris, Demetrios, Barbieri, Isaia, Vijayabaskar, M. S., Liu, Wen-Hsin, Gozdecka, Malgorzata, Metzakopian, Emmanouil, Toop, Hamish D., Dudek, Monika, Robson, Samuel C., Hermida-Prado, Francisco, Yang, Yu Hsuen, Babaei-Jadidi, Roya, Garyfallos, Dimitrios A., Ponstingl, Hannes, Dias, Joao M. L., Gallipoli, Paolo, Seiler, Michael, Buonamici, Silvia, Vick, Binje, Bannister, Andrew J., Rad, Roland, Prinjha, Rab K., Marioni, John C., Huntly, Brian, Batson, Jennifer, Morris, Jonathan C., Pina, Cristina, Bradley, Allan, Jeremias, Irmela, Bates, David O., Yusa, Kosuke, Kouzarides, Tony, Vassiliou, George S.
Yayımlandı Nat Commun (2018)