Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation

Por Gallipoli, Paolo, Pellicano, Francesca, Morrison, Heather, Laidlaw, Kamilla, Allan, Elaine K., Bhatia, Ravi, Copland, Mhairi, Jørgensen, Heather G., Holyoake, Tessa L.
Publicado em 2013

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

Por Heaney, Nicholas B., Pellicano, Francesca, Zhang, Bin, Crawford, Lisa, Chu, Su, Kazmi, Syed M. A., Allan, Elaine K., Jorgensen, Heather G., Irvine, Alexandra E., Bhatia, Ravi, Holyoake, Tessa L.
Publicado em 2010

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival

Por Hamilton, Ashley, Helgason, G. Vignir, Schemionek, Mirle, Zhang, Bin, Myssina, Svetlana, Allan, Elaine K., Nicolini, Franck E., Müller-Tidow, Carsten, Bhatia, Ravi, Brunton, Valerie G., Koschmieder, Steffen, Holyoake, Tessa L.
Publicado em 2012

ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells

Por Karvela, Maria, Baquero, Pablo, Kuntz, Elodie M., Mukhopadhyay, Arunima, Mitchell, Rebecca, Allan, Elaine K., Chan, Edmond, Kranc, Kamil R., Calabretta, Bruno, Salomoni, Paolo, Gottlieb, Eyal, Holyoake, Tessa L., Helgason, G. Vignir
Publicado no Autophagy (2016)

The Antiproliferative Activity of Kinase Inhibitors in Chronic Myeloid Leukemia Cells Is Mediated by FOXO Transcription Factors

Por Pellicano, Francesca, Scott, Mary T, Helgason, G Vignir, Hopcroft, Lisa E M, Allan, Elaine K, Aspinall-O'Dea, Mark, Copland, Mhairi, Pierce, Andrew, Huntly, Brian J P, Whetton, Anthony D, Holyoake, Tessa L
Publicado no Stem Cells (2014)