Isolation and therapeutic potential of human haemopoietic stem cells

Por Clark, Andrew D., Jørgensen, Heather G., Mountford, Joanne, Holyoake, Tessa L.
Publicado em 2003

Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation

Por Gallipoli, Paolo, Pellicano, Francesca, Morrison, Heather, Laidlaw, Kamilla, Allan, Elaine K., Bhatia, Ravi, Copland, Mhairi, Jørgensen, Heather G., Holyoake, Tessa L.
Publicado em 2013

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34(+) cells in vitro and in vivo

Por Gallipoli, Paolo, Cook, Amy, Rhodes, Susan, Hopcroft, Lisa, Wheadon, Helen, Whetton, Anthony D., Jørgensen, Heather G., Bhatia, Ravi, Holyoake, Tessa L.
Publicado em 2014

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells

Por Zhang, Bin, Chu, Su, Agarwal, Puneet, Campbell, Victoria L., Hopcroft, Lisa, Jørgensen, Heather G., Lin, Allen, Gaal, Karl, Holyoake, Tessa L., Bhatia, Ravi
Publicado no Blood (2016)

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression

Por Tarafdar, Anuradha, Hopcroft, Lisa E. M., Gallipoli, Paolo, Pellicano, Francesca, Cassels, Jennifer, Hair, Alan, Korfi, Koorosh, Jørgensen, Heather G., Vetrie, David, Holyoake, Tessa L., Michie, Alison M.
Publicado no Blood (2017)

Nano‐curcumin safely prevents streptozotocin‐induced inflammation and apoptosis in pancreatic beta cells for effective management of Type 1 diabetes mellitus

Por Ganugula, Raghu, Arora, Meenakshi, Jaisamut, Patcharawalai, Wiwattanapatapee, Ruedeekorn, Jørgensen, Heather G, Venkatpurwar, Vinod P, Zhou, Beiyan, Rodrigues Hoffmann, Aline, Basu, Rita, Guo, Shaodong, Majeti, Naga Venkata Ravi Kumar
Publicado no Br J Pharmacol (2017)

Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells

Por Heaney, Nicholas B., Pellicano, Francesca, Zhang, Bin, Crawford, Lisa, Chu, Su, Kazmi, Syed M. A., Allan, Elaine K., Jorgensen, Heather G., Irvine, Alexandra E., Bhatia, Ravi, Holyoake, Tessa L.
Publicado em 2010

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia

Por Laidlaw, Kamilla M.E., Berhan, Samuel, Liu, Suhu, Silvestri, Giovannino, Holyoake, Tessa L., Frank, David A., Aggarwal, Bharat, Bonner, Michael Y., Perrotti, Danilo, Jørgensen, Heather G., Arbiser, Jack L.
Publicado no Oncotarget (2016)

Properties of CD34(+) CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate

Por Jiang, Xiaoyan, Forrest, Donna, Nicolini, Franck, Turhan, Ali, Guilhot, Joelle, Yip, Calvin, Holyoake, Tessa, Jorgensen, Heather, Lambie, Karen, Saw, Kyi Min, Pang, Emily, Vukovic, Ranko, Lehn, Paeta, Ringrose, Ashley, Yu, Miao, Brinkman, Ryan R., Smith, Clay, Eaves, Allen, Eaves, Connie
Publicado em 2010

Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex

Por Chen, Min, Gallipoli, Paolo, DeGeer, Donna, Sloma, Ivan, Forrest, Donna L., Chan, Matthew, Lai, Damian, Jorgensen, Heather, Ringrose, Ashley, Wang, Hui Mi, Lambie, Karen, Nakamoto, Helen, Saw, Kyi Min, Turhan, Ali, Arlinghaus, Ralph, Paul, James, Stobo, Jon, Barnett, Michael J., Eaves, Allen, Eaves, Connie J, Holyoake, Tessa L., Jiang, Xiaoyan
Publicado em 2013