Assembling defenses against therapy-resistant leukemic stem cells: Bcl6 joins the ranks

por Pellicano, Francesca, Holyoake, Tessa L.
Publicado 2011

Casting a NETwork instead of shooting magic bullets

por Abraham, Sheela A., Holyoake, Tessa L.
Publicado en Cell Cycle (2016)

Preclinical approaches in chronic myeloid leukemia: from cells to systems

por Clarke, Cassie J., Holyoake, Tessa L.
Publicado en Exp Hematol (2017)

Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606

por Konig, Heiko, Holyoake, Tessa L., Bhatia, Ravi
Publicado 2008

Validating a network hub in leukaemia stem cells

por Hopcroft, Lisa E., Abraham, Sheela A., Holyoake, Tessa L.
Publicado en Oncoscience (2017)

Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia

por Jiang, Xiaoyan, Lopez, Angel, Holyoake, Tessa, Eaves, Allen, Eaves, Connie
Publicado 1999

Eradication of Chronic Myeloid Leukemia Stem Cells: A Novel Mathematical Model Predicts No Therapeutic Benefit of Adding G-CSF to Imatinib

por Foo, Jasmine, Drummond, Mark W., Clarkson, Bayard, Holyoake, Tessa, Michor, Franziska
Publicado 2009

Isolation and therapeutic potential of human haemopoietic stem cells

por Clark, Andrew D., Jørgensen, Heather G., Mountford, Joanne, Holyoake, Tessa L.
Publicado 2003

Effects of Dasatinib on Src kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells

por Konig, Heiko, Copland, Mhairi, Chu, Su, Jove, Richard, Holyoake, Tessa L., Bhatia, Ravi
Publicado 2008

Autophagy in Chronic Myeloid Leukaemia: Stem Cell Survival and Implication in Therapy

por Helgason, G. Vignir, Mukhopadhyay, Arunima, Karvela, Maria, Salomoni, Paolo, Calabretta, Bruno, Holyoake, Tessa L.
Publicado en Curr Cancer Drug Targets (2013)

The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells

por Pellicano, Francesca, Šimara, Pavel, Sinclair, Amy, Helgason, G. Vignir, Copland, Mhairi, Grant, Steven, Holyoake, Tessa Laurie
Publicado 2011

Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt–β-catenin signaling

por Zhang, Bin, Li, Min, McDonald, Tinisha, Holyoake, Tessa L., Moon, Randall T., Campana, Dario, Shultz, Leonard, Bhatia, Ravi
Publicado 2013

Autophagy in blood cancers: biological role and therapeutic implications

por Nencioni, Alessio, Cea, Michele, Montecucco, Fabrizio, Longo, Valter D., Patrone, Franco, Carella, Angelo M., Holyoake, Tessa L., Helgason, G. Vignir
Publicado 2013

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemic stem cells

por Kuntz, Elodie M., Baquero, Pablo, Michie, Alison M., Dunn, Karen, Tardito, Saverio, Holyoake, Tessa L., Helgason, G. Vignir, Gottlieb, Eyal
Publicado en Nat Med (2017)

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib

por Li, Ling, Wang, Lisheng, Li, Liang, Wang, Zhiqiang, Ho, Yinwei, McDonald, Tinisha, Holyoake, Tessa L., Chen, WenYong, Bhatia, Ravi
Publicado 2012

Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation

por Gallipoli, Paolo, Pellicano, Francesca, Morrison, Heather, Laidlaw, Kamilla, Allan, Elaine K., Bhatia, Ravi, Copland, Mhairi, Jørgensen, Heather G., Holyoake, Tessa L.
Publicado 2013

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34(+) cells in vitro and in vivo

por Gallipoli, Paolo, Cook, Amy, Rhodes, Susan, Hopcroft, Lisa, Wheadon, Helen, Whetton, Anthony D., Jørgensen, Heather G., Bhatia, Ravi, Holyoake, Tessa L.
Publicado 2014

Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny

por Calaminus, Simon D. J., Guitart, Amelie, Sinclair, Amy, Schachtner, Hannah, Watson, Steve P., Holyoake, Tessa L., Kranc, Kamil R., Machesky, Laura M.
Publicado 2012

Arachidonate 15-lipoxygenase is required for chronic myeloid leukemia stem cell survival

por Chen, Yaoyu, Peng, Cong, Abraham, Sheela A., Shan, Yi, Guo, Zhiru, Desouza, Ngoc, Cheloni, Giulia, Li, Dongguang, Holyoake, Tessa L., Li, Shaoguang
Publicado 2014

Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia

por Zhang, Bin, Ho, Yin Wei, Huang, Qin, Maeda, Takahiro, Lin, Allen, Lee, Sung-uk, Hair, Alan, Holyoake, Tessa L., Huettner, Claudia, Bhatia, Ravi
Publicado 2012