Accelerating cancer evolution: a dark side of SIRT1 in genome maintenance

Por Chen, WenYong
Publicado em 2012

Emerging Roles of SIRT1 in Cancer Drug Resistance

Por Wang, Zhiqiang, Chen, WenYong
Publicado em 2013

Roles of SIRT1 in leukemogenesis

Por Chen, WenYong, Bhatia, Ravi
Publicado em 2013

Sorting out functions of sirtuins in cancer

Por Roth, Mendel, Chen, WenYong
Publicado no Oncogene (2013)

A convenient cell culture model for CML acquired resistance through BCR-ABL mutations

Por Wang, Zhiqiang, Chen, WenYong
Publicado no Methods Mol Biol (2016)

Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation

Por Chen, Wen Yong, Townes, Tim M.
Publicado em 2000

The emerging and diverse roles of sirtuins in cancer: a clinical perspective

Por Yuan, Hongfeng, Su, Leila, Chen, Wen Yong
Publicado em 2013

Sirtuins in Hematological Aging and Malignancy

Por Roth, Mendel, Wang, Zhiqiang, Chen, WenYong
Publicado em 2013

SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cells

Por Roth, Mendel, Wang, Zhiqiang, Chen, Wen Yong
Publicado no Oncotarget (2016)

CD150(−) side population defines leukemia stem cells in a BALB/C mouse model of CML and is depleted by genetic loss of SIRT1

Por Wang, Zhiqiang, Chen, Ching-Cheng, Chen, WenYong
Publicado no Stem Cells (2015)

Overcoming CML acquired resistance by specific inhibition of Aurora A kinase in the KCL-22 cell model

Por Yuan, Hongfeng, Wang, Zhiqiang, Zhang, Hao, Roth, Mendel, Bhatia, Ravi, Chen, Wen Yong
Publicado em 2012

SIRT1 deacetylase promotes acquisition of genetic mutations for drug resistance in CML cells

Por Wang, Zhiqiang, Yuan, Hongfeng, Roth, Mendel, Stark, Jeremy M., Bhatia, Ravi, Chen, WenYong
Publicado em 2012

Trichostatin A Up-Regulates Human Papillomavirus Type 11 Upstream Regulatory Region-E6 Promoter Activity in Undifferentiated Primary Human Keratinocytes

Por Zhao, Wei, Noya, Francisco, Chen, Wen Yong, Townes, Tim M., Chow, Louise T., Broker, Thomas R.
Publicado em 1999

Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase

Por Chen, Wen Yong, Bailey, Evans C., McCune, Steven L., Dong, Jian-Yun, Townes, Tim M.
Publicado em 1997

Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis

Por Yuan, Hongfeng, Wang, Zhiqiang, Li, Ling, Zhang, Hao, Modi, Hardik, Horne, David, Bhatia, Ravi, Chen, WenYong
Publicado em 2012

BCR-ABL Gene Expression Is Required for Its Mutations in a Novel KCL-22 Cell Culture Model for Acquired Resistance of Chronic Myelogenous Leukemia

Por Yuan, Hongfeng, Wang, Zhiqiang, Gao, Chunggang, Chen, Wengang, Huang, Qin, Yee, Jiing-Kuan, Bhatia, Ravi, Chen, WenYong
Publicado em 2010

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib

Por Li, Ling, Wang, Lisheng, Li, Liang, Wang, Zhiqiang, Ho, Yinwei, McDonald, Tinisha, Holyoake, Tessa L., Chen, WenYong, Bhatia, Ravi
Publicado em 2012

ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance

Por Wang, Zhiqiang, Liu, Zheng, Wu, Xiwei, Chu, Su, Wang, Jinhui, Yuan, Hongfeng, Roth, Mendel, Yuan, Yate-Ching, Bhatia, Ravi, Chen, WenYong
Publicado em 2014

Chronic myelogenous leukemia stem and progenitor cells demonstrate chromosomal instability related to repeated breakage-fusion-bridge cycles mediated by increased nonhomologous end...

Por Chakraborty, Sujata, Stark, Jeremy M., Sun, Can-Lan, Modi, Hardik, Chen, WenYong, O'Connor, Timothy R., Forman, Stephen J., Bhatia, Smita, Bhatia, Ravi
Publicado em 2012

Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling

Por Nam, Sangkil, Scuto, Anna, Yang, Fan, Chen, WenYong, Park, Sungman, Yoo, Hwa-Seung, Konig, Heiko, Bhatia, Ravi, Cheng, Xinlai, Merz, Karl-Heinz, Eisenbrand, Gerhard, Jove, Richard
Publicado em 2012