Wird geladen...

Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation

Virally transduced genes are often silenced after integration into the host genome. Chromatin immunoprecipitation and nuclease sensitivity experiments now demonstrate that silencing of the transgene is characterized by deacetylation of histone H4 lysines and chromatin condensation. Trichostatin A tr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chen, Wen Yong, Townes, Tim M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26671/
https://ncbi.nlm.nih.gov/pubmed/10618426
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!