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Overcoming CML acquired resistance by specific inhibition of Aurora A kinase in the KCL-22 cell model
Serine/threonine kinase Aurora A is essential for regulating mammalian cell division and is overexpressed in many types of human cancer. However, the role of Aurora A in chemoresistance of chronic myelogenous leukemia (CML) is not well understood. Using the KCL-22 cell culture model we have recently...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271265/ https://ncbi.nlm.nih.gov/pubmed/22116466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr278 |
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