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A convenient cell culture model for CML acquired resistance through BCR-ABL mutations
Tyrosine kinase inhibitors (TKIs) are the effective treatments for chronic myeloid leukemia (CML). However, clinical resistance to TKIs that leads to patient relapse remains a challenge. Acquisition of BCR-ABL mutations is crucial in the resistance but the underlying molecular mechanisms are poorly...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010030/ https://ncbi.nlm.nih.gov/pubmed/27581146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-4011-0_13 |
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