Mutated BCR-ABL Generates Immunogenic T Cell Epitopes In CML Patients

PURPOSE: Characterization of an approach to identify leukemia neoantigens arising in the context of drug resistance. EXPERIMENTAL DESIGN: We assessed whether leukemia neoantigens could be generated from drug-resistant mutations in BCR-ABL following imatinib relapse in chronic myelogenous leukemia (C...

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Detalhes bibliográficos
Main Authors: Cai, Ann, Keskin, Derin B., DeLuca, David S., Alonso, Anselmo, Zhang, Wandi, Zhang, Guang Lan, Hammond, Naa Norkor, Nardi, Valentina, Stone, Richard M., Neuberg, Donna, Sidney, John, Brusic, Vladimir, Wu, Catherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759991/
https://ncbi.nlm.nih.gov/pubmed/22912393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1182
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