Mutated BCR-ABL Generates Immunogenic T Cell Epitopes In CML Patients

PURPOSE: Characterization of an approach to identify leukemia neoantigens arising in the context of drug resistance. EXPERIMENTAL DESIGN: We assessed whether leukemia neoantigens could be generated from drug-resistant mutations in BCR-ABL following imatinib relapse in chronic myelogenous leukemia (C...

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Detaylı Bibliyografya
Asıl Yazarlar: Cai, Ann, Keskin, Derin B., DeLuca, David S., Alonso, Anselmo, Zhang, Wandi, Zhang, Guang Lan, Hammond, Naa Norkor, Nardi, Valentina, Stone, Richard M., Neuberg, Donna, Sidney, John, Brusic, Vladimir, Wu, Catherine J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759991/
https://ncbi.nlm.nih.gov/pubmed/22912393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-1182
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