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CD150(−) side population defines leukemia stem cells in a BALB/C mouse model of CML and is depleted by genetic loss of SIRT1
Leukemia stem cells (LSCs) of chronic myeloid leukemia (CML) are refractory to tyrosine kinase inhibitor treatment, persist in the residual disease and are important source for disease recurrence. Better understanding CML LSCs will help devise new strategies to eradicate these cells. The BALB/c mous...
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| 出版年: | Stem Cells |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713280/ https://ncbi.nlm.nih.gov/pubmed/26466808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2218 |
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