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CD150(−) side population defines leukemia stem cells in a BALB/C mouse model of CML and is depleted by genetic loss of SIRT1

Leukemia stem cells (LSCs) of chronic myeloid leukemia (CML) are refractory to tyrosine kinase inhibitor treatment, persist in the residual disease and are important source for disease recurrence. Better understanding CML LSCs will help devise new strategies to eradicate these cells. The BALB/c mous...

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Vydáno v:Stem Cells
Hlavní autoři: Wang, Zhiqiang, Chen, Ching-Cheng, Chen, WenYong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713280/
https://ncbi.nlm.nih.gov/pubmed/26466808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2218
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